Description

Quin 2 Potassium Hydrate is a high-purity, cell-permeable chelator and fluorescent indicator specifically designed for the quantitative measurement of intracellular free calcium ions (Ca²⁺). This compound matters for researchers and industrial developers requiring precise, real-time monitoring of calcium dynamics in biological systems, a critical parameter in numerous physiological and pathological processes. It is essential for professionals in pharmaceutical research, biochemical assay development, and cell biology, where accurate intracellular signaling data is paramount.

Application

• Intracellular Calcium Ion (Ca²⁺) Sensing: Primary use as a fluorescent probe for quantifying free cytosolic Ca²⁺ concentrations in live cells.
• Cell Signaling Pathway Research: Investigating calcium's role as a second messenger in processes like muscle contraction, neurotransmitter release, and gene expression.
• Drug Discovery & Toxicology Screening: Used in high-throughput assays to evaluate compound effects on cellular calcium homeostasis.
• Neuroscience and Cardiac Research: Monitoring calcium transients in neurons and cardiomyocytes to study excitability and contractility.
• Biochemical Reagent Manufacturing: A key component in the formulation of diagnostic kits and research-grade assay buffers.
• Academic and Industrial R&D: Fundamental tool for basic research in physiology and applied research in biotechnology.

Basic Information

Product Name	Quin 2 Potassium Hydrate
CAS No.	149022-19-5
Molecular Formula	C₂₄H₂₀N₂O₈ · xK⁺ · yH₂O
Molecular Weight	Contact for details
Synonyms	Quin-2 Potassium Salt; Quin2 K⁺ Salt; 2-[[2-Bis(carboxymethyl)amino-5-methylphenoxy]methyl]-6-methoxy-8-bis(carboxymethyl)aminoquinoline Potassium Salt; 2-{[2-[Bis(carboxymethyl)amino]-5-methylphenoxy]methyl}-6-methoxy-8-[bis(carboxymethyl)amino]quinoline Potassium Salt; Quin-2/AM precursor salt; Intracellular calcium indicator Quin-2; Q-2 Potassium Hydrate
EINECS	Contact for details

Quality Control

Our Quin 2 Potassium Hydrate is produced under stringent conditions to ensure batch-to-batch consistency and high performance in sensitive applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and the absence of interfering impurities. A Certificate of Analysis (COA) detailing specific lot results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and performance. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Fluorescence Properties	Conforms to reference standard
Solubility	Soluble in aqueous buffer, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.