Description

Harmol Hydrochloride Dihydrate is a high-purity chemical reference standard and research compound. This material is critical for analytical and pharmacological studies, serving as a key intermediate and standard in the development and quality control of active pharmaceutical ingredients. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and quality control departments requiring precise and reliable reference materials.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and impurity profiling of related drug substances and finished products in HPLC and other analytical methods.
• Biochemical Research: Employed as a tool compound in pharmacological studies to investigate enzyme interactions and receptor binding assays.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic building block in the production of more complex pharmaceutical compounds.
• Quality Control & Assurance: Essential for calibrating analytical equipment and validating test methods in GMP and non-GMP laboratory environments.
• Metabolite Studies: Utilized in research focusing on drug metabolism and pharmacokinetics (DMPK) to understand metabolic pathways.

Basic Information

Product Name	Harmol Hydrochloride Dihydrate
CAS No.	149022-16-2
Molecular Formula	C12H12N2O•HCl•2H2O
Molecular Weight	270.71 g/mol
Synonyms	1-Methyl-9H-pyrido[3,4-b]indol-7-ol hydrochloride dihydrate; 7-Hydroxy-1-methyl-9H-pyrido[3,4-b]indole hydrochloride dihydrate; Harmol HCl dihydrate; 1-Methylharmol hydrochloride dihydrate
EINECS	Contact for details

Quality Control

Our Harmol Hydrochloride Dihydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and control of specific impurities, to ensure it meets the stringent requirements for research and reference standard applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	11.0% - 14.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.