Description

20-Hydroxylipoxin B4 is a specialized lipoxin metabolite, a potent bioactive lipid mediator derived from arachidonic acid. This compound is of significant interest for its role in advanced research on the resolution of inflammation and immune modulation. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for biochemical studies, drug discovery, and as a reference standard.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of eicosanoid signaling pathways and inflammation resolution mechanisms.
• Drug Discovery & Development: Serves as a key intermediate or target molecule in the development of novel anti-inflammatory and pro-resolving therapeutics.
• Cell Signaling Studies: Applied in in vitro and in vivo models to investigate receptor interactions and downstream cellular effects of specialized pro-resolving mediators (SPMs).
• Academic & Institutional Research: Essential for universities and research institutes conducting fundamental research in immunology, pharmacology, and lipidomics.
• Diagnostic Development: Potential use in the calibration and development of assays (e.g., ELISA, LC-MS/MS) for detecting lipid mediators in biological samples.

Basic Information

Product Name	20-Hydroxylipoxin B4
CAS No.	148942-81-8
Molecular Formula	C₂₀H₃₂O₆
Molecular Weight	368.47 g/mol
Synonyms	20-OH-LXB4; 20-Hydroxy Lipoxin B4; 5S,14R,15S-Trihydroxy-6E,8Z,10E,12E-eicosatetraenoic Acid; Lipoxin B4 metabolite; 20-Hydroxy LXB4; 20(R/S)-HETE-derived Lipoxin; (5S,14R,15S)-Trihydroxy-6E,8Z,10E,12E-eicosatetraenoic Acid
EINECS	Contact for details

Quality Control

Our 20-Hydroxylipoxin B4 is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity confirmation, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.