Description

Dehydrodolichol is a polyprenol derivative, a key intermediate in the biosynthesis of dolichol phosphate, which plays a critical role in protein N-glycosylation pathways. This compound matters for researchers and manufacturers focused on studying and manipulating cellular glycosylation processes, which are fundamental to protein folding, cell signaling, and immune response. It is primarily needed by the life science research, pharmaceutical development, and biotechnology industries for use as a biochemical reagent and a reference standard in metabolic studies.

Application

• Biochemical Research: Used as a critical intermediate in studies of the dolichol phosphate cycle and protein N-glycosylation.
• Enzyme Substrate: Serves as a substrate for enzymes like dehydrodolichyl diphosphate synthase in metabolic pathway analysis.
• Pharmaceutical Development: Investigated as a reference compound for developing therapies targeting glycosylation disorders.
• Cell Biology Studies: Employed in research on endoplasmic reticulum function and lipid-linked oligosaccharide biosynthesis.
• Metabolic Pathway Mapping: Utilized as a tracer or standard in mass spectrometry-based metabolomics.
• Academic Research: A key reagent for universities and institutes studying glycobiology and post-translational modifications.

Basic Information

Product Name	Dehydrodolichol
CAS No.	148879-95-2
Molecular Formula	C100H164O
Molecular Weight	1381.4 g/mol
Synonyms	Dehydrodolichyl alcohol; (all-E)-3,7,11,15,19,23,27,31,35,39,43,47,51,53-Tetradecamethyltetrapentaconta-2,6,10,14,18,22,26,30,34,38,42,46,50,54-tetradecaen-1-ol; Polyprenol derivative; Dolichol precursor; Dehydrodolichol (C100)
EINECS	Contact for details

Quality Control

Our Dehydrodolichol is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation. Keep the container in a cool, dry, and well-ventilated area, away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.