Description

Mant-Gppnhp Triethylammonium Salt is a high-purity, specialized nucleotide analog derivative used in advanced biochemical research and pharmaceutical development. This compound is critical for studying and manipulating cellular signaling pathways, particularly those involving cyclic nucleotides. It serves as a valuable building block and research tool for scientists in pharmaceutical R&D, biotechnology, and academic research focused on enzymology, molecular biology, and drug discovery.

Application

• Biochemical Research: As a substrate or inhibitor in enzymatic assays for studying phosphodiesterases (PDEs) and other nucleotide-metabolizing enzymes.
• Pharmaceutical Development: A key intermediate in the synthesis of novel therapeutic agents targeting cyclic nucleotide signaling pathways.
• Molecular Biology: Used in the study of intracellular second messenger systems, such as cyclic GMP (cGMP) and cyclic AMP (cAMP) pathways.
• Proteomics & Drug Discovery: Employed in high-throughput screening (HTS) platforms to identify new drug candidates for cardiovascular, neurological, and inflammatory diseases.
• Diagnostic Reagent Manufacturing: A component in the formulation of specialized diagnostic kits for research and clinical analysis.

Basic Information

Product Name	Mant-Gppnhp Triethylammonium Salt
CAS No.	148821-01-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	MANT-GppNHp triethylammonium salt; 2'/3'-O-(N-Methylanthraniloyl)-guanosine-5'-[β,γ-imido]triphosphate triethylammonium salt; MANT-caged GppNHp; MANT-Gpp(NH)p; Fluorescent GTP analog; Non-hydrolyzable GTPγS analog; Mant-guanosine 5'-[β,γ-imido]triphosphate
EINECS	Contact for details

Quality Control

Our Mant-Gppnhp Triethylammonium Salt is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, Methanol, Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.