Description

Octyl Thiomaltoside is a high-purity, non-ionic surfactant and detergent specifically designed for the solubilization and stabilization of membrane proteins. Its unique thioglycosidic linkage provides enhanced chemical stability compared to conventional maltosides, making it a critical reagent for structural biology and biochemical research. This product is essential for scientists and manufacturers in the biopharmaceutical, academic research, and diagnostic sectors who require reliable, high-quality detergents for challenging membrane protein work.

Application

• Solubilization of integral membrane proteins for structural analysis (e.g., X-ray crystallography, Cryo-EM).
• Stabilization of purified membrane proteins in solution for functional and biophysical studies.
• Component of lysis buffers for the extraction of membrane-bound receptors and enzymes.
• Use in the reconstitution of membrane proteins into lipid bilayers or nanodiscs.
• Critical reagent in the production and purification of membrane protein-based therapeutics and vaccines.
• Applications in diagnostic assay development requiring stable membrane protein targets.

Basic Information

Product Name	Octyl Thiomaltoside
CAS No.	148616-91-5
Molecular Formula	C20H38O10S
Molecular Weight	470.57 g/mol
Synonyms	n-Octyl β-D-thiomaltoside; Octyl 1-Thio-β-D-maltopyranoside; OTM; n-Octylthiomaltoside; Thiomaltoside Octyl Ether; 1-S-Octyl-1-thio-β-D-maltopyranoside; 4-O-α-D-Glucopyranosyl-1-thio-β-D-glucopyranose Octyl Derivative
EINECS	Contact for details

Quality Control

Our Octyl Thiomaltoside is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and critical impurities. We adhere to relevant quality guidelines for research-grade biochemicals to support your compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of water.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Critical Micelle Concentration (CMC)	0.2 - 0.4 mM (in water at 25°C)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.