Description

5-Formylcytidine is a modified nucleoside of significant interest in biochemical and pharmaceutical research. This compound serves as a critical intermediate and a valuable building block for the synthesis of more complex nucleoside analogs and oligonucleotides. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleic acid chemistry, drug discovery, and the development of novel therapeutic agents.

Application

• Nucleic Acid Research: Used as a modified cytidine derivative to study RNA structure, function, and epigenetic modifications.
• Pharmaceutical Intermediates: Serves as a key synthetic precursor in the development of antiviral and anticancer nucleoside drugs.
• Oligonucleotide Synthesis: Employed in the solid-phase synthesis of labeled or modified oligonucleotides for diagnostic and research applications.
• Bioconjugation: The formyl group provides a reactive handle for conjugation with amines, enabling the creation of labeled probes or drug delivery systems.
• Enzymatic Studies: Acts as a substrate or inhibitor for enzymes involved in nucleotide metabolism and RNA modification pathways.
• Reference Standard: Used as a high-purity analytical standard in quality control and method development for related pharmaceutical products.

Basic Information

Product Name	5-Formylcytidine
CAS No.	148608-53-1
Molecular Formula	C10H13N3O6
Molecular Weight	271.23 g/mol
Synonyms	5-Formylcytidine; 5-FoCyd; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde; Cytidine, 5-formyl-; 5-Formyl-cytidine; 5-Carbaldehydecytidine
EINECS	Contact for details

Quality Control

Our 5-Formylcytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.