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n-Undecyl-B-D-Thiomaltoside CAS NO 148565-57-5
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CAS No.:148565-57-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-Undecyl-B-D-Thiomaltoside is a high-purity, non-ionic thioglycoside surfactant derived from maltose. This specialized compound is valued for its ability to solubilize and stabilize membrane proteins without denaturation, making it a critical reagent in structural biology and biochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in protein crystallization, membrane protein extraction, and biophysical analysis.
Application
- Membrane Protein Solubilization: Essential for extracting and stabilizing integral membrane proteins from lipid bilayers for structural studies.
- Protein Crystallization: Used as a detergent in crystallization screens to facilitate the formation of high-quality protein crystals for X-ray diffraction.
- Biophysical Characterization: Employed in techniques such as Surface Plasmon Resonance (SPR) and cryo-electron microscopy (cryo-EM) to maintain protein native state.
- Lipid Nanodisc Formation: Acts as a tool for reconstituting membrane proteins into native-like lipid environments for functional assays.
- Pharmaceutical Research: Used in drug discovery pipelines targeting membrane-bound receptors and transporters.
- Reference Standard: Serves as an analytical standard in quality control for biochemical reagent production.
Basic Information
| Product Name | n-Undecyl-B-D-Thiomaltoside |
| CAS No. | 148565-57-5 |
| Molecular Formula | C23H44O10S |
| Molecular Weight | 512.66 g/mol |
| Synonyms | Undecyl-β-D-thiomaltoside; n-Undecyl-β-D-thiomaltopyranoside; UDM; 1-Undecyl-β-D-thiomaltoside; Thiomaltoside C11; n-Undecyl 4-O-α-D-Glucopyranosyl-β-D-thioglucopyranoside; 4-O-α-D-Glucopyranosyl-1-decyl-1-thio-β-D-glucopyranoside; Anagrade Detergent UDM |
| EINECS | Contact for details |
Quality Control
Our n-Undecyl-B-D-Thiomaltoside is manufactured under strict quality systems to ensure batch-to-batch consistency for sensitive research applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and critical micelle concentration (CMC). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Critical Micelle Concentration (CMC) | 0.29 mM (Typical in water at 25°C) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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