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n-Undecyl-B-D-Thiomaltoside CAS NO 148565-57-5


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CAS No.:148565-57-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Undecyl-B-D-Thiomaltoside is a high-purity, non-ionic thioglycoside surfactant derived from maltose. This specialized compound is valued for its ability to solubilize and stabilize membrane proteins without denaturation, making it a critical reagent in structural biology and biochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in protein crystallization, membrane protein extraction, and biophysical analysis.

Application

  • Membrane Protein Solubilization: Essential for extracting and stabilizing integral membrane proteins from lipid bilayers for structural studies.
  • Protein Crystallization: Used as a detergent in crystallization screens to facilitate the formation of high-quality protein crystals for X-ray diffraction.
  • Biophysical Characterization: Employed in techniques such as Surface Plasmon Resonance (SPR) and cryo-electron microscopy (cryo-EM) to maintain protein native state.
  • Lipid Nanodisc Formation: Acts as a tool for reconstituting membrane proteins into native-like lipid environments for functional assays.
  • Pharmaceutical Research: Used in drug discovery pipelines targeting membrane-bound receptors and transporters.
  • Reference Standard: Serves as an analytical standard in quality control for biochemical reagent production.

Basic Information

Product Name n-Undecyl-B-D-Thiomaltoside
CAS No. 148565-57-5
Molecular Formula C23H44O10S
Molecular Weight 512.66 g/mol
Synonyms Undecyl-β-D-thiomaltoside; n-Undecyl-β-D-thiomaltopyranoside; UDM; 1-Undecyl-β-D-thiomaltoside; Thiomaltoside C11; n-Undecyl 4-O-α-D-Glucopyranosyl-β-D-thioglucopyranoside; 4-O-α-D-Glucopyranosyl-1-decyl-1-thio-β-D-glucopyranoside; Anagrade Detergent UDM
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Quality Control

Our n-Undecyl-B-D-Thiomaltoside is manufactured under strict quality systems to ensure batch-to-batch consistency for sensitive research applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and critical micelle concentration (CMC). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Critical Micelle Concentration (CMC) 0.29 mM (Typical in water at 25°C)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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