Description

Decyl-β-D-1-Thiomaltopyranoside is a high-purity, non-ionic thioglycoside surfactant derived from maltose. This specialized compound is valued for its ability to solubilize and stabilize membrane proteins without denaturation, making it a critical reagent in structural biology and biophysical research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require reliable, high-quality detergents for challenging protein purification and crystallization workflows.

Application

• Membrane Protein Solubilization: A key detergent for extracting and solubilizing integral membrane proteins from lipid bilayers while maintaining native conformation.
• Structural Biology: Critical for preparing stable protein samples for X-ray crystallography, cryo-electron microscopy (cryo-EM), and NMR spectroscopy.
• Biophysical Studies: Used in fluorescence spectroscopy, isothermal titration calorimetry (ITC), and surface plasmon resonance (SPR) to study protein-ligand interactions in a membrane-mimetic environment.
• Vaccine and Therapeutic Development: Employed in the formulation and stabilization of membrane protein-based vaccines and biotherapeutics.
• Diagnostic Assay Development: Serves as a stabilizing agent for membrane-bound receptors and enzymes used in diagnostic kits and high-throughput screening.
• Liposome and Nanodisc Preparation: Facilitates the formation and loading of model membrane systems for drug delivery and functional studies.

Basic Information

Product Name	Decyl-β-D-1-Thiomaltopyranoside
CAS No.	148565-56-4
Molecular Formula	C22H42O10S
Molecular Weight	498.63 g/mol
Synonyms	Decyl β-D-thiomaltoside; n-Decyl-β-D-thiomaltoside; DTM; Decyl-Thiomaltoside; n-Decyl 1-Thio-β-D-maltopyranoside; 1-S-Decyl-1-thio-β-D-maltopyranoside; 1-Thio-β-D-maltopyranoside, decyl; Octyl S-Galactopyranosyl-(1→4)-1-thio-β-D-glucopyranoside derivative
EINECS	Contact for details

Quality Control

Our Decyl-β-D-1-Thiomaltopyranoside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the exacting standards required for sensitive research and development applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Biological Activity (CMC)	Reported

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.