Description

1,2-Dibutyryl-Sn-Glycero-3-Phosphoinositol CAS NO 148504-92-1 is a synthetic, cell-permeable derivative of phosphatidylinositol, a key phospholipid in cellular signaling pathways. This compound is a critical biochemical tool for researchers studying intracellular signal transduction, particularly within the phosphoinositide cycle. It is primarily utilized in life science research and pharmaceutical development for investigating lipid-mediated signaling mechanisms, enzyme kinetics, and receptor interactions. The compound's defined structure allows for precise manipulation and observation of downstream biological effects.

Application

• Biochemical Research: As a substrate or inhibitor in enzymatic assays to study the activity of phospholipases, kinases, and phosphatases involved in inositol phosphate metabolism.
• Cell Signaling Studies: To probe and modulate intracellular phosphatidylinositol signaling pathways, including those related to cell growth, proliferation, and differentiation.
• Pharmaceutical Screening: Used in high-throughput screening (HTS) platforms to identify and characterize novel drug candidates targeting lipid-signaling enzymes and receptors.
• Metabolic Pathway Analysis: As a tracer or labeled compound in metabolic studies to elucidate the biosynthesis and turnover of phosphoinositides.
• Enzyme Mechanism Investigation: Provides insights into the substrate specificity and catalytic mechanisms of enzymes that process phosphatidylinositol derivatives.
• Academic & Industrial R&D: A fundamental reagent for basic and applied research in molecular biology, biochemistry, and drug discovery laboratories worldwide.

Basic Information

Product Name	1,2-Dibutyryl-Sn-Glycero-3-Phosphoinositol
CAS No.	148504-92-1
Molecular Formula	C23H41O14P
Molecular Weight	572.54 g/mol
Synonyms	1,2-Dibutyryl-sn-glycero-3-phospho-(1D-myo-inositol); 1,2-Dibutyryl-rac-glycero-3-phosphoinositol; PI(4,5)P2 analog (dibutyryl); sn-Glycero-3-phosphoinositol 1,2-dibutyrate; Dibutyryl phosphatidylinositol; 1,2-Di-O-butyryl-sn-glycero-3-phospho-(1D-myo-inositol); Synthetic Phosphatidylinositol derivative; Cell-permeable PI analog
EINECS	Contact for details

Quality Control

Our 1,2-Dibutyryl-Sn-Glycero-3-Phosphoinositol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including chromatographic purity assessment and structural confirmation. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform, DMSO, ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.