Description

12-Methylleukotriene B3 is a specialized leukotriene analog of significant interest in biochemical and pharmacological research. This compound is a valuable reference standard and synthetic intermediate for investigating inflammatory pathways and developing targeted therapeutics. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors for advanced studies in immunology and drug discovery.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of leukotriene biosynthesis, metabolism, and receptor interactions.
• Pharmaceutical Development: Serves as a critical intermediate in the synthesis of novel anti-inflammatory drug candidates and receptor antagonists.
• In Vitro Diagnostics: Employed in the development and calibration of immunoassays and analytical methods for detecting inflammatory mediators.
• Academic Research: A key tool for university and institutional labs exploring the molecular mechanisms of inflammation, allergy, and related diseases.
• Metabolite Studies: Used in metabolic pathway analysis to understand the role of methylated leukotriene derivatives in cellular signaling.

Basic Information

Product Name	12-Methylleukotriene B3
CAS No.	148504-32-9
Molecular Formula	C21H32O4
Molecular Weight	348.48 g/mol
Synonyms	(5S,6Z,8E,10E,12R,14Z)-12-Methyl-5-hydroxyicosa-6,8,10,14-tetraenoic acid; 12(R)-Methyl-LTB3; 12-Methyl leukotriene B3; 12-Me-LTB3; 12-Methyl LTB3; 12R-Methylleukotriene B3; 12-Methyl-5(S),12(R)-dihydroxy-6,8,10,14-eicosatetraenoic acid
EINECS	Contact for details

Quality Control

Our 12-Methylleukotriene B3 is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be provided to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, keep desiccated to minimize degradation. Allow the sealed container to reach room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 1.0% (KF)
Solvent Residues	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.