Description

1,2-Dihexanoyl-Sn-Glycero-3-Phosphoinositol is a synthetic, high-purity phospholipid derivative, specifically a phosphoinositol analog with defined acyl chains. This compound is a critical biochemical tool for studying cellular signaling pathways, particularly those involving phosphatidylinositol and its role in membrane biology. It is essential for researchers and manufacturers in pharmaceutical development, lipidomics research, and the production of advanced liposomal drug delivery systems.

Application

• Biochemical Research: As a key substrate or standard for investigating phosphoinositide-specific phospholipase C (PI-PLC) and other lipid-modifying enzyme activities.
• Lipidomics & Metabolomics: Used as a reference standard in mass spectrometry for the identification and quantification of complex cellular lipids.
• Drug Delivery Systems: A functional excipient for formulating specialized liposomes and lipid nanoparticles (LNPs) targeting specific intracellular pathways.
• Cell Signaling Studies: Employed in cell culture models to modulate or trace phosphatidylinositol signaling cascades involved in growth, proliferation, and apoptosis.
• Diagnostic Reagent Development: A component in enzymatic assay kits for the detection and measurement of inositol phosphate metabolites.
• Membrane Biophysics: Used to create model membranes (e.g., vesicles, bilayers) for studying protein-lipid interactions and membrane dynamics.

Basic Information

Product Name	1,2-Dihexanoyl-Sn-Glycero-3-Phosphoinositol
CAS No.	148437-41-6
Molecular Formula	C21H39O13P
Molecular Weight	530.50 g/mol
Synonyms	1,2-Dihexanoyl-sn-glycero-3-phospho-(1D-myo-inositol); PI(6:0/6:0); Phosphatidylinositol dihexanoate; 1,2-Dihexanoylphosphatidylinositol; DHPI; sn-Glycero-3-phosphoinositol 1,2-dihexanoate; myo-Inositol, 1-(1,2-dihexanoyl-sn-glycero-3-phospho)-, (1D)-
EINECS	Contact for details

Quality Control

Our 1,2-Dihexanoyl-Sn-Glycero-3-Phosphoinositol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for structural confirmation, and NMR for identity verification, ensuring it meets the exacting standards required for life science research. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere. Allow the sealed vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 2.0 %
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.