Description

Uridine 5'-Diphospho-Galuronic Acid Trisodium is a high-purity nucleotide sugar derivative, serving as a critical activated donor substrate for glycosyltransferases. This compound is essential for the biosynthesis of glycosaminoglycans and other complex carbohydrates in biological systems. It is primarily utilized by researchers and manufacturers in the fields of biochemistry, enzymology, and pharmaceutical development, particularly for studying and synthesizing glycoconjugates.

Application

• Enzymatic Synthesis: Key substrate for in vitro enzymatic synthesis of hyaluronic acid, chondroitin sulfate, and other glycosaminoglycans (GAGs).
• Biochemical Research: Used as a critical reagent in studies of glycosyltransferase kinetics, specificity, and inhibition mechanisms.
• Pharmaceutical Intermediates: Serves as a building block in the research and development of novel glycoprotein-based therapeutics and vaccines.
• Diagnostic Kit Development: Employed in the formulation of assay kits for measuring glycosyltransferase activity in clinical and research settings.
• Cell Culture & Tissue Engineering: Used in media supplements to study the role of specific glycosylation patterns in cell signaling and extracellular matrix formation.
• Metabolic Pathway Analysis: A vital tool for tracing and understanding nucleotide sugar metabolism in various disease models.

Basic Information

Item	Detail
Product Name	Uridine 5'-Diphospho-Galuronic Acid Trisodium
CAS No.	148407-07-2
Molecular Formula	C15H21N2Na3O18P2
Molecular Weight	688.21 g/mol (anhydrous basis)
Synonyms	UDP-Galuronic Acid Trisodium Salt; UDP-GalA Trisodium; UDP-α-D-Galacturonic Acid Trisodium Salt; Uridine 5'-(trihydrogen diphosphate) P'→5'-ester with α-D-galactopyranuronic acid, trisodium salt; UDP-D-Galacturonic Acid Na3; 5'-UDP-GalA Trisodium
EINECS	Contact for details

Quality Control

Our Uridine 5'-Diphospho-Galuronic Acid Trisodium is manufactured under strict quality controls to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines for production and quality management systems to meet the stringent requirements of the biopharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the material desiccated. Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
pH (1% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg
Biological Activity	Conforms (Enzymatic Assay)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.