Description

3'-C-Methyluridine Diphosphate is a chemically modified nucleotide diphosphate analog, a key building block in advanced biochemical research and development. This compound is essential for studying and manipulating RNA structure, function, and metabolism due to its specific modification at the ribose sugar. It is primarily utilized by researchers and manufacturers in the fields of nucleic acid chemistry, enzymology, and pharmaceutical development, particularly for creating novel therapeutic agents and diagnostic tools.

Application

• Biochemical Research: As a substrate or inhibitor for studying RNA polymerases, nucleotidyltransferases, and other nucleotide-processing enzymes.
• Antiviral Drug Development: Investigation as a potential nucleotide analog for incorporation into RNA chains to inhibit viral replication.
• Enzyme Mechanism Studies: Probing the active sites and catalytic mechanisms of enzymes that utilize uridine derivatives.
• Synthetic Biology: Used in the synthesis of modified RNA oligonucleotides with altered properties for therapeutic or diagnostic applications.
• Metabolic Pathway Analysis: Tracing and understanding nucleotide salvage and metabolic pathways in cellular systems.
• Pharmaceutical Intermediates: Serving as a critical precursor in the synthesis of more complex nucleoside-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3'-C-Methyluridine Diphosphate
CAS No.	148253-83-2
Molecular Formula	C10H15N2O12P2
Molecular Weight	417.18 g/mol
Synonyms	3'-C-Methyl-UDP; 3'-Methyluridine 5'-diphosphate; UDP, 3'-C-methyl-; 3'-C-Methyluridine 5'-(trihydrogen diphosphate); 3'-Methyluridine diphosphate; 5'-O-[(phosphonooxy)phosphinyl]-3'-C-methyluridine
EINECS	Contact for details

Quality Control

Our 3'-C-Methyluridine Diphosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.