Description

1,2-Dipalmitoyl-3-Docosahexaenoyl Glycerol is a structured triglyceride (TAG) where palmitic acid (C16:0) occupies the sn-1 and sn-2 positions and the ω-3 fatty acid docosahexaenoic acid (DHA, C22:6) is esterified at the sn-3 position. This specific molecular architecture is designed to mimic human milk fat and is critical for enhancing the bioavailability and targeted delivery of DHA, a nutrient essential for neurological and visual development. It is a key ingredient for advanced nutritional science, serving manufacturers in the infant formula, pharmaceutical, and nutraceutical sectors who require precise lipid structures for clinical and nutritional applications.

Application

• Infant Formula & Human Milk Fat Substitutes (HMFS): As a primary structured lipid to closely replicate the fatty acid profile and positional distribution found in breast milk, supporting optimal growth and cognitive development.
• Pharmaceutical Excipients & Drug Delivery Systems: Utilized in lipid-based formulations such as self-emulsifying drug delivery systems (SEDDS) and nanoparticles to improve the solubility and absorption of poorly water-soluble active pharmaceutical ingredients (APIs).
• Clinical Nutrition & Medical Foods: Incorporated into enteral and parenteral nutrition products to provide a bioavailable source of DHA for patients with specific metabolic needs or malabsorption issues.
• High-End Nutraceuticals & Dietary Supplements: Used in premium ω-3 supplements and functional foods where enhanced DHA absorption and metabolic benefits are required.
• Biochemical & Nutritional Research: Serves as a standard or reagent in studies investigating lipid metabolism, brain development, and the functional effects of structured triglycerides.
• Cosmeceuticals: Applied in advanced skincare formulations for its potential emollient properties and role in supporting skin barrier function.

Basic Information

Product Name	1,2-Dipalmitoyl-3-Docosahexaenoyl Glycerol
CAS No.	147965-31-9
Molecular Formula	C55H96O6
Molecular Weight	853.4 g/mol
Synonyms	1,2-Dipalmitoyl-3-docosahexaenoyl-rac-glycerol; DHA-TAG (sn-2 Palmitate); TAG (16:0/16:0/22:6); Structured Triglyceride OPO (DHA variant); Glycerol 1,2-dipalmitate 3-(4,7,10,13,16,19-docosahexaenoate); sn-OPO (DHA); DPP-DHA; 1,2-Dihexadecanoyl-3-docosahexaenoyl-sn-glycerol
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoyl-3-Docosahexaenoyl Glycerol is manufactured under strict quality management systems. Each batch is characterized using advanced analytical techniques to ensure identity, purity, and positional specificity of the fatty acids. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as regioisomeric purity, DHA content, and oxidation status. Production can adhere to cGMP guidelines for pharmaceutical and food-grade applications, ensuring traceability and compliance with global regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store unopened containers at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture condensation. Once opened, use promptly and purge the container with inert gas before resealing.

Specification

Item	Specification
Appearance	Colorless to pale yellow oily liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0% (Total TAG)
Regioisomeric Purity (sn-2 Palmitate)	≥ 90.0%
DHA Content (GC)	≥ 22.0% (of total fatty acids)
Peroxide Value (PV)	≤ 5.0 meq/kg
Anisidine Value (p-AV)	≤ 20.0
Acid Value	≤ 1.0 mg KOH/g
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.