Description

Biotin-36-Dc7Atp CAS NO 147958-08-5 is a high-purity, modified nucleotide analog designed for advanced biochemical research and diagnostic applications. This compound is critical for labeling and detection technologies, offering superior specificity and sensitivity in molecular assays. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in genomics, proteomics, and high-throughput screening.

Application

• Nucleic Acid Labeling: Used as a biotinylated ATP analog for enzymatic incorporation into DNA or RNA probes for non-radioactive detection.
• Diagnostic Assay Development: A key component in the manufacture of ELISA, microarray, and other molecular diagnostic kits for pathogen or genetic mutation detection.
• Pull-down Assays & Affinity Purification: Enables the isolation and purification of specific proteins, nucleic acids, or complexes using streptavidin-biotin interaction.
• Next-Generation Sequencing (NGS): Employed in sequencing-by-synthesis platforms and library preparation workflows.
• Cell Signaling & Kinase Research: Serves as a substrate or tracer in studies involving ATP-dependent enzymes like kinases and polymerases.
• In Situ Hybridization (ISH/FISH): Enhances signal amplification for high-resolution visualization of genetic material in cells and tissues.

Basic Information

Product Name	Biotin-36-Dc7Atp
CAS No.	147958-08-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Biotin-36-Deoxycytidine-7-Aminotriphosphate; Biotin-dC7-ATP; 7-Deaza-2'-deoxyadenosine-5'-triphosphate, N6-(6-((6-((biotinoyl)amino)hexanoyl)amino)hexyl)-; Biotinylated dC7ATP; Biotin-36-dC7-ATP; N6-(6-((6-(5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)hexyl)-7-deaza-2'-deoxyadenosine-5'-triphosphate
EINECS	Contact for details

Quality Control

Our Biotin-36-Dc7Atp is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation, to ensure it meets the exacting standards required for sensitive research and in vitro diagnostic (IVD) use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Biological Activity	Functional in enzymatic incorporation assays

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.