Description

C8-Hsl CAS NO 147852-84-4 is a high-purity synthetic homoserine lactone derivative, specifically N-octanoyl-L-homoserine lactone, which serves as a key signaling molecule in bacterial quorum sensing. This compound is critical for researchers and developers studying microbial communication, biofilm formation, and the development of novel anti-infective strategies. It is primarily utilized in the life sciences sector for biochemical research, pharmaceutical development, and as a reference standard in analytical laboratories.

Application

• Quorum Sensing Research: As a potent autoinducer for studying cell-to-cell communication in Gram-negative bacteria, particularly in Pseudomonas aeruginosa and other pathogens.
• Biofilm Studies: Used to induce and investigate biofilm formation, a major factor in bacterial virulence and antibiotic resistance.
• Pharmaceutical Development: Serves as a target molecule or inhibitor scaffold in the discovery of novel anti-virulence drugs and quorum sensing inhibitors (QSIs).
• Microbial Physiology: Employed in laboratory experiments to elucidate the regulatory mechanisms controlling virulence factor production and bioluminescence.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in HPLC, LC-MS, and other chromatographic systems.
• Agricultural Research: Applied in studies aimed at disrupting pathogenic bacterial communication in crops to develop alternative plant protection agents.

Basic Information

Product Name	C8-Hsl
CAS No.	147852-84-4
Molecular Formula	C12H21NO3
Molecular Weight	227.30 g/mol
Synonyms	N-Octanoyl-L-homoserine lactone; N-(3-Oxooctanoyl)-L-homoserine lactone; C8-AHL; OHL; N-Capryloyl-L-homoserine lactone; 3-Oxo-C8-HSL; Pseudomonas aeruginosa autoinducer; N-Octanoylhomoserine lactone; 3-Oxo-N-octanoylhomoserine lactone
EINECS	Contact for details

Quality Control

Every batch of C8-Hsl (CAS 147852-84-4) is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC and NMR, to ensure high chemical purity and structural identity, meeting the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, consider storing under argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.