Description

Octyl 2-Acetamido-2-Deoxy-B-D-Glucopyranoside is a high-purity, non-ionic alkyl glycoside surfactant specifically designed for biochemical and pharmaceutical research. This compound is valued for its ability to solubilize membrane proteins while maintaining their native structure and function, a critical requirement for structural biology and drug discovery. It is an essential reagent for scientists and manufacturers in the biotechnology, pharmaceutical development, and life sciences sectors who require reliable, high-quality detergents for challenging protein purification and crystallization workflows.

Application

• Membrane Protein Solubilization and Stabilization: Critical for extracting and maintaining the activity of integral membrane proteins from cellular membranes for downstream analysis.
• Structural Biology Studies: Used in the crystallization of membrane proteins for X-ray crystallography and cryo-electron microscopy (cryo-EM) to determine 3D structures.
• Biophysical Characterization: Employed in techniques like surface plasmon resonance (SPR), isothermal titration calorimetry (ITC), and nuclear magnetic resonance (NMR) to study protein-ligand interactions.
• Pharmaceutical Formulation: Acts as a stabilizing excipient in the development of biologic drug products that involve sensitive protein components.
• Cell Lysis and Extraction Buffers: A key component in gentle lysis buffers for isolating membrane-bound organelles or protein complexes without denaturation.
• Chromatography: Used in mobile phases or sample preparation for the purification of membrane proteins via size-exclusion or affinity chromatography.

Basic Information

Item	Details
Product Name	Octyl 2-Acetamido-2-Deoxy-B-D-Glucopyranoside
CAS No.	147126-58-7
Molecular Formula	C₁₆H₃₁NO₇
Molecular Weight	349.42 g/mol
Synonyms	n-Octyl-β-D-glucopyranoside derivative; Octyl N-Acetyl-β-D-glucosaminide; β-Octyl N-acetylglucosaminide; Octyl GlcNAc; O-GlcNAc octyl ether; 2-Acetamido-2-deoxy-β-D-glucopyranoside octyl ether; N-Acetyl-β-D-glucosaminide octyl; (2R,3R,4R,5S,6R)-2-(Acetamidomethyl)-6-(octyloxy)tetrahydro-2H-pyran-3,4,5-triol
EINECS	Contact for details

Quality Control

Every batch of Octyl 2-Acetamido-2-Deoxy-B-D-Glucopyranoside is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for research-grade biochemicals. Our quality system includes verification of identity, purity, and critical physical parameters. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your laboratory's quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Optical Rotation	-20° to -25° (c=1 in H₂O)
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.