Description

Dodecyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside is a high-purity, non-ionic surfactant and detergent derived from N-acetylglucosamine. This compound is valued for its ability to solubilize membrane proteins while maintaining their native structure and function, making it a critical reagent in structural biology and biochemistry. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in protein purification, crystallization, and functional analysis.

Application

• Membrane Protein Solubilization and Purification: Essential for extracting and stabilizing integral membrane proteins from cellular membranes for downstream analysis.
• Structural Biology Studies: Used in the preparation of protein samples for techniques like X-ray crystallography and cryo-electron microscopy (cryo-EM).
• Biochemical Assay Development: Serves as a mild detergent in activity assays to maintain enzyme functionality without denaturation.
• Lipid Raft Research: Employed in the study of membrane microdomains due to its selective solubilization properties.
• Vaccine and Therapeutic Protein Formulation: Can be used as a stabilizing excipient in biopharmaceutical formulations.
• Cell Lysis and Organelle Isolation: Provides effective yet gentle disruption of cell membranes for organelle preparation.

Basic Information

Product Name	Dodecyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside
CAS No.	147025-06-7
Molecular Formula	C₂₀H₃₉NO₇
Molecular Weight	405.53 g/mol
Synonyms	n-Dodecyl-β-D-glucopyranoside N-acetylglucosamine; Dodecyl N-Acetyl-β-D-glucosaminide; Lauryl N-Acetyl-β-D-glucosaminide; β-Dodecyl GlcNAc; n-Dodecyl 2-acetamido-2-deoxy-β-D-glucopyranoside; 2-Acetamido-2-deoxy-β-D-glucopyranoside dodecyl ether; Dodecyl β-GlcNAc; Detergent β-GlcNAc-C12
EINECS	Contact for details

Quality Control

Our Dodecyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.