Description

Decyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside is a high-purity, non-ionic surfactant and detergent belonging to the alkyl glycoside family, specifically a decyl glycoside derivative of N-acetylglucosamine. This compound is valued for its effective solubilization of membrane proteins while maintaining their native structure and function, making it a critical reagent in structural biology and biochemistry research. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies engaged in protein purification and characterization.

Application

• Membrane Protein Solubilization: Essential for extracting and stabilizing integral membrane proteins from biological membranes for biochemical and biophysical studies.
• Structural Biology: Used in the preparation of protein samples for techniques such as X-ray crystallography, cryo-electron microscopy (cryo-EM), and NMR spectroscopy.
• Biochemical Assays: Serves as a mild detergent in functional assays to study enzyme kinetics, receptor-ligand interactions, and other protein activities in vitro.
• Chromatography: Employed in purification protocols, including affinity and size-exclusion chromatography, to maintain protein solubility and monodispersity.
• Vaccine & Therapeutic Development: Used in the research and development phase for formulating and studying membrane protein-based vaccines and biologics.
• Cell Lysis: An effective component in lysis buffers for gentle disruption of cell membranes to isolate organelles or cytoplasmic contents.

Basic Information

Product Name	Decyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside
CAS No.	147025-05-6
Molecular Formula	C₁₈H₃₅NO₇
Molecular Weight	377.48 g/mol
Synonyms	Decyl N-Acetyl-β-D-glucosaminide; n-Decyl 2-Acetamido-2-deoxy-β-D-glucopyranoside; Decyl GlcNAc; C10-β-GlcNAc; n-Decyl β-D-GlcNAc; 2-Acetamido-2-deoxy-β-D-glucopyranoside decyl ether; Octyl homologue of n-Octyl-β-D-GlcNAc
EINECS	Contact for details

Quality Control

Our Decyl 2-Acetamido-2-Deoxy-β-D-Glucopyranoside is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Quality is verified through rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.