Description

Ondansetron Hydrochloride is a high-purity pharmaceutical active ingredient, a potent and selective serotonin 5-HT3 receptor antagonist. It is a critical component in the formulation of antiemetic medications used to prevent nausea and vomiting. This compound is essential for pharmaceutical manufacturers and research institutions developing treatments for patients undergoing chemotherapy, radiotherapy, or surgery.

Application

• Pharmaceutical API: Primary active ingredient in prescription antiemetic drugs, tablets, and oral solutions.
• Oncology Supportive Care: Formulated to prevent and treat chemotherapy-induced nausea and vomiting (CINV).
• Post-Operative Care: Used in medications to manage nausea and vomiting following surgical procedures.
• Radiotherapy-Induced Nausea: Key component in therapies for patients undergoing radiation treatment.
• Research & Development: Reference standard and building block for novel therapeutic research in gastroenterology and CNS disorders.
• Generic Drug Manufacturing: Sourcing for the production of bioequivalent generic versions of antiemetic medications.

Basic Information

Product Name	Ondansetron Hydrochloride
CAS No.	146844-89-5
Molecular Formula	C18H19N3O·HCl
Molecular Weight	365.84 g/mol
Synonyms	Ondansetron HCl; 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride; GR 38032F; Zofran (as hydrochloride salt); SN 307; (±)-Ondansetron hydrochloride
EINECS	Contact for details

Quality Control

Our Ondansetron Hydrochloride is manufactured under strict quality systems. It undergoes rigorous analytical testing to ensure compliance with major pharmacopoeial standards, including USP and EP monographs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory filings and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.