Description

Noc-12 CAS NO 146724-89-2 is a high-purity chemical compound widely utilized as a nitric oxide donor in advanced biochemical and pharmacological research. Its ability to reliably release nitric oxide under controlled conditions makes it a critical reagent for studying cellular signaling pathways and vascular physiology. This product is essential for research and development laboratories in the pharmaceutical, biotechnology, and life sciences sectors, where precise and consistent chemical performance is paramount.

Application

• Biochemical Research: A key tool for investigating the role of nitric oxide (NO) in cellular communication, signal transduction, and enzyme regulation.
• Pharmacological Studies: Used in vitro and ex vivo to model NO-mediated effects, supporting drug discovery for cardiovascular, neurological, and inflammatory conditions.
• Vascular Biology: Employed to study vasodilation, blood pressure regulation, and endothelial function in experimental settings.
• Neuroscience Research: Facilitates the study of NO as a neurotransmitter and its effects on synaptic plasticity and neural protection.
• Cell Culture & Assay Development: Serves as a standardized NO source for developing and validating high-throughput screening assays and cell-based models.

Basic Information

Product Name	Noc-12
CAS No.	146724-89-2
Molecular Formula	C12H21N7O6 • xH2O
Molecular Weight	359.34 g/mol (anhydrous basis)
Synonyms	NOC-12; 1-Hydroxy-2-oxo-3-(3-aminopropyl)-3-methyl-1-triazene; DETA NONOate; Diethylenetriamine NONOate; (Z)-1-[N-(3-Aminopropyl)-N-(n-propyl)amino]diazen-1-ium-1,2-diolate; 3-Ethylaminopropylsydnone imine; DETA/NO; NO Donor DETA NONOate
EINECS	Contact for details

Quality Control

Every batch of Noc-12 is manufactured and tested under strict quality management protocols to ensure exceptional purity and batch-to-batch consistency, suitable for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay purity, identity confirmation, and impurity profiles. Our quality system is designed to meet the rigorous standards expected in pharmaceutical and biochemical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term stability, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.