Description

Makaluvamine A is a pyrroloiminoquinone alkaloid of significant interest in pharmaceutical research and development. This compound matters due to its potent biological activity, serving as a valuable reference standard and a key scaffold for novel drug discovery. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors focusing on oncology and infectious disease therapeutics.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of drug substances and products in method development and validation.
• Oncology Research: Serves as a critical lead compound and biochemical tool in the study of anticancer mechanisms and the development of new chemotherapeutic agents.
• Antimicrobial Agent Development: Investigated for its potential in creating new classes of antibiotics and antifungals.
• Biochemical Pathway Analysis: Employed as a specific inhibitor or probe to study cellular processes and enzyme functions in life science research.
• High-Throughput Screening (HTS): Utilized in compound libraries for the discovery of new bioactive molecules with similar or enhanced properties.
• Academic & Contract Research: Essential for universities and CROs conducting fundamental research on marine natural products and their synthetic analogs.

Basic Information

Product Name	Makaluvamine A
CAS No.	146555-78-4
Molecular Formula	C₁₈H₁₃N₅O₂
Molecular Weight	331.33 g/mol
Synonyms	Makaluvamine A; 1H-Pyrrolo[2,3-f]quinoline-6,9-dione, 2,3,4,5-tetrahydro-7-methoxy-2,5-dimethyl-8-(phenylmethyl)-; 8-Benzyl-7-methoxy-2,5-dimethyl-2,3,4,5-tetrahydro-1H-pyrrolo[2,3-f]quinoline-6,9-dione
EINECS	Contact for details

Quality Control

Our Makaluvamine A is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Orange to red solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Water Content	≤ 1.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.