Description

Iv(3)-Neuac-Iii(6)-Neuac-Lcose4Cer CAS NO 146358-72-7 is a complex, high-purity ganglioside derivative, specifically a disialylated lacto-series glycosphingolipid. This compound is a critical biochemical tool and reference standard for advanced research in glycobiology and cell signaling. It is essential for scientists and manufacturers in the pharmaceutical and biotechnology sectors who require precise molecular probes for studying carbohydrate-protein interactions, neural development, and immunomodulatory pathways.

Application

• Glycobiology Research: Serves as a high-purity reference standard and substrate for studying sialyltransferase and glycosidase enzyme activities.
• Neuroscience Studies: Used as a critical reagent in investigating the role of complex gangliosides in neuronal cell adhesion, differentiation, and signal transduction.
• Immunology & Vaccine Development: Acts as a target antigen or hapten in the development of diagnostic assays and conjugate vaccines targeting specific carbohydrate epitopes.
• Biomarker Discovery: Employed in mass spectrometry and chromatography as a standard for identifying and quantifying complex glycolipids in biological samples.
• Pharmaceutical Intermediates: Utilized in the synthesis of more complex glycoconjugates and potential therapeutic agents targeting cell surface receptors.
• Diagnostic Kit Manufacturing: Incorporated as a key component in ELISA and other immunoassay kits for the detection of specific antibodies or antigens.

Basic Information

Product Name	Iv(3)-Neuac-Iii(6)-Neuac-Lcose4Cer
CAS No.	146358-72-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	IV3NeuAcIII6NeuAcLcOse4Cer; Disialosyl-lactoneotetraosylceramide; Ganglioside, disialosyl-lactoneotetraosyl-; Lactoneotetraosylceramide, IV3-α-NeuAc, III6-α-NeuAc-; Disialylated Lc4Cer; NeuAc-α-2-3-Gal-β-1-3-GlcNAc-β-1-3-Gal-β-1-4-Glc-β-1-1-Cer (with NeuAc-α-2-6 on GlcNAc); 146358-72-7
EINECS	Contact for details

Quality Control

Our Iv(3)-Neuac-Iii(6)-Neuac-Lcose4Cer is produced under stringent quality management systems. Each batch undergoes comprehensive analytical characterization using techniques such as NMR, HPLC, and mass spectrometry to ensure structural identity and high purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to cGMP principles for research-grade biochemicals to ensure consistency and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.