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13-Propylthio-5-Hydroxy-6-Deoxytetracycline CAS NO 146277-96-5


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CAS No.:146277-96-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

13-Propylthio-5-Hydroxy-6-Deoxytetracycline is a chemically modified tetracycline derivative, a class of compounds renowned for their broad-spectrum antibiotic activity. This specific derivative is engineered to enhance stability and target specificity, making it a valuable intermediate in advanced pharmaceutical research and development. It is primarily sought by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis of novel antibacterial agents and for investigating structure-activity relationships.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of next-generation tetracycline-class antibiotics.
  • Antibacterial Research: Used in microbiological and biochemical studies to explore new mechanisms of action against resistant bacterial strains.
  • Medicinal Chemistry: Serves as a core scaffold for the development and optimization of novel antimicrobial compounds.
  • Veterinary Medicine Development: Investigated for potential applications in animal health products.
  • Biochemical Tool Compound: Utilized in laboratory settings to study bacterial protein synthesis inhibition.
  • Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name 13-Propylthio-5-Hydroxy-6-Deoxytetracycline
CAS No. 146277-96-5
Molecular Formula C₂₄H₃₁N₂O₈S
Molecular Weight 507.58 g/mol
Synonyms 13-Propylthio-5-hydroxy-6-deoxytetracycline; 5-Hydroxy-13-propylthio-6-deoxytetracycline; 6-Deoxy-5-hydroxy-13-propylthiotetracycline; PTDT; Propylthiotetracycline derivative; Tetracycline, 13-(propylthio)-5-hydroxy-6-deoxy-; (4S,4aR,5S,5aR,6S,12aS)-4-(Dimethylamino)-5,10,11,12a-tetrahydroxy-13-(propylthio)-6-methyl-1,12-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
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Quality Control

Our 13-Propylthio-5-Hydroxy-6-Deoxytetracycline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item Specification
Appearance Yellow to light brown powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 95.0%
Related Substances (HPLC) Total impurities ≤ 5.0%
Water Content (KF) ≤ 5.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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