Description

n-Acetyl-9-o-Acetylneuraminic Acid 4-Aminophenylthioketoside is a chemically modified sialic acid derivative designed for advanced biochemical research and development. This compound serves as a critical intermediate and tool for studying carbohydrate-protein interactions, particularly in the context of sialidase inhibitors and glycan synthesis. It is primarily utilized by research institutions and pharmaceutical companies focused on virology, immunology, and the development of novel glycotherapeutics.

Application

• Biochemical Research: A key intermediate in the synthesis of sialidase (neuraminidase) inhibitors for studying influenza and other viral mechanisms.
• Glycobiology Studies: Used as a substrate or inhibitor in enzymatic assays to investigate sialic acid metabolism and cell surface recognition events.
• Pharmaceutical Development: Serves as a building block for creating novel glycoconjugate vaccines and therapeutic agents targeting sialic acid-binding pathogens.
• Diagnostic Reagent Synthesis: Employed in the development of diagnostic tools and probes for detecting specific carbohydrate-binding proteins or pathogens.
• Enzyme Mechanism Analysis: Acts as a tool compound for probing the active sites and catalytic mechanisms of neuraminidases and sialyltransferases.

Basic Information

Product Name	n-Acetyl-9-o-Acetylneuraminic Acid 4-Aminophenylthioketoside
CAS No.	146117-12-6
Molecular Formula	C21H28N2O11S
Molecular Weight	516.52 g/mol
Synonyms	4-Aminophenyl 5-Acetamido-3,5-dideoxy-9-O-acetyl-D-glycero-D-galacto-non-2-ulopyranosidonic Acid 1-Thioketoside; 4-Aminophenyl 5-Acetamido-3,5-dideoxy-9-O-acetyl-D-glycero-D-galacto-non-2-ulopyranosonate 1-Thioketoside; 4-Aminophenyl Thioketoside of N-Acetyl-9-O-acetylneuraminic Acid; Sialic Acid Derivative; Neuraminic Acid Thioketoside; Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our n-Acetyl-9-o-Acetylneuraminic Acid 4-Aminophenylthioketoside is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.