Description

Tetradecanedioic Acid, 1-(2,5-Dioxo-1-Pyrrolidinyl) Ester is a high-purity, bifunctional chemical intermediate designed for advanced synthesis. Its core value lies in its dual reactivity, offering a long-chain diacid backbone coupled with an activated ester group for efficient coupling reactions under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, polymer, and specialty chemical industries seeking to develop novel materials, prodrugs, or high-performance additives.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in creating prodrugs or modifying drug molecules to enhance solubility or bioavailability.
• Polymer Modification: Used as a cross-linking agent or chain extender in polyamide, polyester, and polyurethane systems to improve thermal stability and mechanical properties.
• Specialty Surfactants & Lubricants: Serves as a precursor for synthesizing high-performance, biodegradable surfactants and synthetic lubricants with excellent low-temperature properties.
• Bioconjugation & Linker Chemistry: The activated N-hydroxysuccinimide (NHS) ester moiety enables efficient, gentle conjugation of amines, making it valuable for creating antibody-drug conjugates (ADCs), diagnostic probes, and biomaterials.
• Cosmetic & Personal Care Ingredients: Intermediate for producing emollients and conditioning agents in high-end cosmetic formulations.
• Advanced Material Research: Employed in R&D for developing novel dendritic polymers, liquid crystals, and other functional organic materials.

Basic Information

Product Name	Tetradecanedioic Acid, 1-(2,5-Dioxo-1-Pyrrolidinyl) Ester
CAS No.	146004-82-2
Molecular Formula	C20H33NO6
Molecular Weight	383.48 g/mol
Synonyms	1,14-Tetradecanedioic Acid N-Hydroxysuccinimide Ester; Tetradecanedioic Acid Bis(N-succinimidyl) Ester (partial); NHS Ester of Tetradecanedioic Acid; 1,14-Bis(2,5-dioxopyrrolidin-1-yl) tetradecanedioate; Succinimidyl Tetradecanedioate; C14-Di-NHS; Long-chain di-NHS ester; Tetradecanedioic Acid Di(N-succinimidyl) Ester; 1,14-Di-O-succinimidyl Tetradecanedioate
EINECS	Contact for details

Quality Control

Our Tetradecanedioic Acid, 1-(2,5-Dioxo-1-Pyrrolidinyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach ambient temperature before opening to prevent condensation and moisture ingress. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Assay	95.0 - 102.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.