Description

[1,3]Dioxolo[4,5-J]Phenanthridin-6(2H)-One, 1,3,4,4A,5,11B-Hexahydro-2,3,4-Trihydroxy-, (2S,3R,4S,4Ar,11Br)- is a complex, stereochemically defined alkaloid derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block or potential intermediate for the development of novel pharmaceuticals and bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of complex natural products, drug discovery, and the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the multi-step synthesis of potential therapeutic agents, particularly in alkaloid chemistry.
• Organic Synthesis Building Block: Used in advanced research for constructing complex polycyclic frameworks with multiple stereocenters.
• Medicinal Chemistry Research: Employed as a scaffold or intermediate for structure-activity relationship (SAR) studies in drug discovery programs.
• Natural Product Synthesis: Acts as a synthetic target or intermediate in the total synthesis of complex natural products containing phenanthridine or related heterocyclic cores.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	[1,3]Dioxolo[4,5-J]Phenanthridin-6(2H)-One, 1,3,4,4A,5,11B-Hexahydro-2,3,4-Trihydroxy-, (2S,3R,4S,4Ar,11Br)-
CAS No.	145987-74-2
Molecular Formula	C₁₅H₁₅NO₆
Molecular Weight	305.28 g/mol
Synonyms	(2S,3R,4S,4aR,11bR)-1,3,4,4a,5,11b-Hexahydro-2,3,4-trihydroxy[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one; Hexahydro-2,3,4-trihydroxy[1,3]dioxolo[4,5-j]phenanthridin-6-one (stereoisomer); 1,3,4,4a,5,11b-Hexahydro-2,3,4-trihydroxy[1,3]dioxolo[4,5-j]phenanthridin-6(2H)-one; NSC 339579; Alkaloid C-Hexahydro Trihydroxy Dioxolophenanthridinone Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material suitable for research and development purposes, with purity typically verified by advanced chromatographic and spectroscopic methods. Certificates of Analysis (COA) detailing identity, purity, and related substances are available upon request. For specific pharmacopeial (e.g., USP) or custom grade requirements, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.