Description

Oxathiolan 5Fu-.B. is a specialized fluorinated nucleoside analog derivative, identified by CAS No. 145986-11-4. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its role as a key intermediate or active pharmaceutical ingredient (API) in antiviral and anticancer therapies. It is primarily required by pharmaceutical manufacturers, biotechnology research institutions, and fine chemical synthesis laboratories engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer drugs.
• Antiviral Drug Research: Used in the development of nucleoside analog-based treatments targeting viral polymerases.
• Oncology Research: Investigated as a potential active component or prodrug in chemotherapy regimens.
• Biochemical Research: Employed in studies of enzyme inhibition, cellular metabolism, and mechanism of action.
• Fine Chemical Synthesis: Utilized in multi-step organic syntheses requiring protected or modified nucleoside structures.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	Oxathiolan 5Fu-.B.
CAS No.	145986-11-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5-Fluoro-1-[(2S,5R)-5-(hydroxymethyl)-1,3-oxathiolan-2-yl]pyrimidine-2,4(1H,3H)-dione; 5-Fluoro-1-[(2S,5R)-5-(hydroxymethyl)-1,3-oxathiolan-2-yl]uracil; 5-Fluoro-3'-thia-2',3'-dideoxycytidine related compound; FTC related intermediate; Emtricitabine related analog; Oxathiolane fluorouracil derivative; 5-Fluoro-oxathiolane nucleoside
EINECS	Contact for details

Quality Control

Our Oxathiolan 5Fu-.B. is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis to ensure compliance with ICH guidelines and customer-specific requirements. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.