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1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-L-Serine (Monosodium Salt) CAS NO 145849-32-7
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CAS No.:145849-32-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-L-Serine (Monosodium Salt) is a high-purity, synthetic phospholipid derivative, specifically a phosphatidylserine (PS) species. This compound is a critical building block for constructing biomimetic membranes and liposomal drug delivery systems, offering superior batch-to-batch consistency for research and formulation. It is essential for pharmaceutical developers, academic researchers, and manufacturers in the advanced drug delivery, diagnostic, and cosmetic industries who require reliable, well-characterized lipid excipients.
Application
- Liposomal Drug Delivery Systems: A key component for creating anionic, stealth, or targeted liposomes to enhance drug solubility, stability, and cellular uptake.
- Biomimetic Membrane Research: Used in model membrane studies (e.g., vesicles, supported lipid bilayers) to investigate cell signaling, protein-lipid interactions, and membrane biophysics.
- Pharmaceutical Formulations: Serves as a functional excipient in injectable and topical formulations where membrane fusion or specific charge characteristics are required.
- Diagnostic Reagents: Employed in the development of diagnostic assays and imaging agents that rely on lipid-based nanoparticles.
- Cosmetic Actives: Incorporated into high-end skincare products for its purported role in supporting skin barrier function and cellular membrane health.
- Biochemical Research: A standard reagent for studying apoptosis, blood coagulation, and other serine-phospholipid-mediated cellular processes.
Basic Information
| Product Name | 1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-L-Serine (Monosodium Salt) |
| CAS No. | 145849-32-7 |
| Molecular Formula | C38H74NO10PNa |
| Molecular Weight | 758.96 g/mol |
| Synonyms | DPPS (sodium salt); 1,2-Dihexadecanoyl-sn-glycero-3-phospho-L-serine sodium salt; L-α-Phosphatidylserine (DPPS, Na salt); Phosphatidylserine (16:0/16:0) sodium salt; PS (16:0/16:0) sodium salt; Sodium 1,2-dipalmitoyl-sn-glycero-3-phosphoserine; 1,2-Dipalmitoylphosphatidylserine sodium salt |
| EINECS | Contact for details |
Quality Control
Our 1,2-Dipalmitoyl-Sn-Glycero-3-Phospho-L-Serine (Monosodium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, related substances, and other critical parameters are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or solid |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Heavy Metals | ≤ 20 ppm |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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