Description

2,2'-[[(Aminohydroxyphosphinyl)Imino]Di-2,1-Ethanediyl]Bis[L-γ-Glutamyl-L-Cysteinylglycine] is a specialized, high-purity synthetic peptide derivative of significant interest in advanced biochemical research and development. Its unique structure, incorporating a phosphinyl imino linkage and multiple amino acid residues, makes it a valuable precursor or intermediate for studying enzyme inhibition, signal transduction pathways, and targeted therapeutic applications. This compound is primarily utilized by research institutions and pharmaceutical developers focused on novel drug discovery, particularly in areas involving metalloproteinase activity and chelation chemistry.

Application

• Biochemical Research: Serves as a critical reference standard or synthetic intermediate in proteomics and enzymology studies.
• Pharmaceutical R&D: Used as a building block or precursor in the synthesis of novel peptide-based drug candidates and prodrugs.
• Enzyme Inhibition Studies: Investigated for its potential role as an inhibitor for specific metalloproteinases due to its structural motifs.
• Chelation Therapy Research: Explored in preclinical research for designing molecules that bind specific metal ions.
• Diagnostic Reagent Development: Potential use in developing specialized assay components or labeled probes for biochemical detection.
• Academic Research: Employed in university laboratories for advanced studies in bioorganic and medicinal chemistry.

Basic Information

Product Name	2,2'-[[(Aminohydroxyphosphinyl)Imino]Di-2,1-Ethanediyl]Bis[L-γ-Glutamyl-L-Cysteinylglycine]
CAS No.	145784-68-5
Molecular Formula	C24H40N8O14P2S2
Molecular Weight	806.70 g/mol
Synonyms	Bis(γ-Glu-Cys-Gly) phosphinyl imino derivative; NSC 339313; L-γ-Glutamyl-L-cysteinylglycine, 2,2'-[[(aminohydroxyphosphinyl)imino]di-2,1-ethanediyl]bis-; Phosphocysteine-Glutathione Conjugate; Aminohydroxyphosphinyl imino bis(glutathione ethyl ester) derivative; GSH-based phosphinyl peptide; (Aminohydroxyphosphinyl)imino-bis(γ-ECG)
EINECS	Contact for details

Quality Control

Our 2,2'-[[(Aminohydroxyphosphinyl)Imino]Di-2,1-Ethanediyl]Bis[L-γ-Glutamyl-L-Cysteinylglycine] is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, critical for research reproducibility. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent internal quality standards and can provide material tailored to specific research-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider under an inert atmosphere such as argon or nitrogen. Allow the sealed container to reach room temperature before opening to minimize condensation and exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Identification (IR)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.