Description

Troxacitabine is a synthetic nucleoside analog with potent antineoplastic activity. This compound is valued for its unique mechanism of action, which involves inhibition of DNA synthesis and chain termination, making it a subject of significant research interest. It is primarily utilized by pharmaceutical R&D teams and academic researchers focused on developing novel oncology therapeutics and studying cellular mechanisms of action.

Application

• Oncology Research & Drug Development: As a key intermediate or active pharmaceutical ingredient (API) in preclinical and clinical research for various cancers.
• Biochemical Research: Used as a tool compound to study nucleoside metabolism, DNA replication inhibition, and apoptosis pathways.
• Antiviral Research: Investigation of its potential activity against viral polymerases due to its nucleoside analog structure.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Mechanistic Studies: Employed in cellular and molecular biology to understand resistance mechanisms and combination therapies in cancer treatment.

Basic Information

Item	Detail
Product Name	Troxacitabine
CAS No.	145511-98-4
Molecular Formula	C9H11FN2O5
Molecular Weight	246.19 g/mol
Synonyms	(-)-2'-Deoxy-3'-oxa-4'-thiocytidine; L-OddC; L-Oxathiolanylcytosine; BCH-4556; Troxatyl; (-)-2'-Deoxy-3'-oxa-4'-thio-5-fluorocytidine; L-(-)-dioxolane-cytidine; 1-[(2S,4S)-2-(Hydroxymethyl)-1,3-oxathiolan-4-yl]-5-fluoropyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our Troxacitabine is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to ensure material integrity for critical research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.