Description

α-Troxacitabine is a synthetic nucleoside analog with significant potential in advanced pharmaceutical research and development. Its primary value lies in its unique mechanism of action as a cytidine analog, making it a compound of high interest for investigating novel therapeutic pathways. This product is essential for research institutions and pharmaceutical companies focused on oncology and antiviral drug discovery. We supply high-purity α-Troxacitabine (CAS NO 145416-37-1) to support critical global R&D efforts.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel nucleoside-based therapeutics.
• Oncology Research: Investigated for its potential antitumor and cytotoxic properties in preclinical cancer studies.
• Antiviral Agent Development: Used in research targeting the development of new antiviral medications.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies involving DNA polymerases or related enzymes.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Mechanistic Studies: Aids in understanding cell cycle arrest and apoptosis mechanisms at the molecular level.

Basic Information

Product Name	α-Troxacitabine
CAS No.	145416-37-1
Molecular Formula	C9H12FN3O5
Molecular Weight	261.21 g/mol
Synonyms	Troxa; BCH-4556; (-)-β-L-1,3-Dioxolane-cytidine, 5-fluoro-; 5-Fluoro-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]cytosine; 1-((2S,4S)-2-(Hydroxymethyl)-1,3-dioxolan-4-yl)-5-fluorocytosine; β-L-Dioxolane-cytidine, 5-fluoro-; L-(-)-Dioxolane-cytidine, 5-fluoro-; Troxacitabine (β-L-isomer)
EINECS	Contact for details

Quality Control

Our α-Troxacitabine is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for pharmaceutical intermediates, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.