Description

α-(3-Hydroxysialyl)Cholesterol is a sophisticated synthetic glycolipid derivative that combines a cholesterol backbone with a sialic acid moiety. This unique molecular architecture is critical for research and development in advanced biomimetic systems and targeted drug delivery platforms. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on glycobiology, membrane studies, and novel therapeutic agent synthesis.

Application

• Biomimetic Membrane Research: As a key component for constructing synthetic lipid bilayers and vesicles to study cell membrane properties and interactions.
• Drug Delivery Systems: Functional excipient for enhancing the targeting and cellular uptake of liposomal and nanoparticle-based therapeutic carriers.
• Glycobiology & Sialic Acid Studies: A valuable reference standard and synthetic intermediate for investigating sialyltransferase activity and sialic acid-mediated biological recognition.
• Diagnostic Reagent Development: Used in the formulation of specialized reagents for detecting specific carbohydrate-protein interactions.
• Vaccine Adjuvant Research: Investigated for its potential immunomodulatory properties in next-generation vaccine formulations.
• Bioconjugation & Chemical Biology: Serves as a building block for creating novel chemical probes and conjugates to label or manipulate biological systems.

Basic Information

Product Name	α-(3-Hydroxysialyl)Cholesterol
CAS No.	145402-49-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cholesteryl 3-Hydroxysialyl Ether; 3-Hydroxysialyl Cholesterol; Sialyl Cholesterol Derivative; Glycolipid Cholesterol Conjugate; N-Acetylneuraminyl Cholesterol; Synthetic Sialylated Lipid; Sialic Acid-Cholesterol Conjugate
EINECS	Contact for details

Quality Control

Our α-(3-Hydroxysialyl)Cholesterol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your critical R&D work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.