Description

Butalbital-D5 is a deuterated internal standard of the pharmaceutical compound butalbital, specifically designed for analytical applications. This high-purity reference material is essential for ensuring the accuracy and reliability of quantitative analysis in complex matrices. It is primarily utilized by analytical chemists and quality control laboratories in the pharmaceutical, forensic, and clinical research sectors for precise method development and validation.

Application

• Primary use as an internal standard for the quantification of butalbital via LC-MS/MS and GC-MS.
• Critical component in method development and validation for pharmaceutical impurity profiling and stability studies.
• Enables accurate pharmacokinetic and bioanalytical studies in clinical research.
• Supports forensic analysis for the definitive identification and measurement of butalbital in toxicology screenings.
• Used in quality control laboratories for assay calibration and ensuring compliance with regulatory standards.
• Facilitates research into drug metabolism and the development of new analytical methodologies.

Basic Information

Product Name	Butalbital-D5
CAS No.	145243-96-5
Molecular Formula	C11H11D5N2O3
Molecular Weight	225.27 g/mol
Synonyms	5-Allyl-5-(2-methylpropyl)-2,4,6(1H,3H,5H)-pyrimidinetrione-1,3-d2,5-d3; Butalbital-d5; 5-Allyl-5-isobutylbarbituric Acid-d5; 5-Allyl-5-(2-methylpropyl)barbituric Acid-d5; Isobutylallylbarbituric Acid-d5; Allylisobutylbarbituric Acid-d5; Deuterated Butalbital (D5)
EINECS	Contact for details

Quality Control

Every batch of Butalbital-D5 is manufactured and tested to meet the stringent requirements for certified reference materials. Our products undergo rigorous quality testing, including advanced spectroscopic and chromatographic methods, to ensure high isotopic purity and chemical identity. Certificates of Analysis (COA) detailing batch-specific results for assay, isotopic enrichment, and purity are provided and traceable to in-house standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D5)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.