Description

5-(3-(Bromoacetamido)Allyl)Uridine-3'-Monophosphate is a chemically modified nucleotide analog designed for advanced biochemical research and development. This compound is a critical reagent for the site-specific labeling and cross-linking of nucleic acids, enabling precise structural and functional studies. It is primarily utilized by researchers and manufacturers in the fields of bioconjugation, structural biology, and pharmaceutical development, particularly for creating probes and targeted therapeutic agents.

Application

• Bioconjugation Reagent: For the covalent attachment of labels, tags, or other molecules to oligonucleotides for diagnostic and research applications.
• Structural Biology Studies: Used in the synthesis of cross-linked nucleic acid probes to investigate RNA/DNA structure, folding, and protein interactions.
• Pharmaceutical R&D: Serves as a key intermediate in the development of nucleotide-based therapeutics, including antisense oligonucleotides and aptamers.
• Probe Synthesis: Enables the creation of highly specific fluorescent or affinity probes for genomic and cellular imaging.
• Chemical Biology Tool: Facilitates the study of nucleic acid metabolism and enzyme mechanisms through targeted modification.
• Material Science: Potential use in the development of functionalized nanomaterials and biosensors.

Basic Information

Product Name	5-(3-(Bromoacetamido)Allyl)Uridine-3'-Monophosphate
CAS No.	144978-95-0
Molecular Formula	C₁₃H₁₇BrN₃O₁₀P
Molecular Weight	510.17 g/mol
Synonyms	5-[3-(Bromoacetamido)allyl]uridine 3'-(dihydrogen phosphate); 5-(3-Bromoacetamidoallyl)UMP; 5-N-[3-(Bromoacetamido)allyl]uridine 3'-monophosphate; BrAc-allyl-UMP; Modified Uridine Monophosphate; Nucleotide Alkylating Agent; Uridine-3'-monophosphate, 5-[3-[(bromoacetyl)amino]-1-propen-1-yl]-
EINECS	Contact for details

Quality Control

Our 5-(3-(Bromoacetamido)Allyl)Uridine-3'-Monophosphate is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.