Description

3-Octadecyloxy-2-Methoxypropylphosphonocholine is a synthetic, high-purity phospholipid derivative with a unique amphiphilic structure. This compound is valued for its ability to form stable, functionalized lipid bilayers and vesicles, making it a critical material for advanced research and formulation development. It is primarily utilized by researchers and product developers in the pharmaceutical, biotechnology, and advanced materials sectors.

Application

• Liposome & Nanoparticle Formulation: A key phospholipid component for constructing drug delivery vehicles, including long-circulating (stealth) liposomes and lipid nanoparticles (LNPs) for mRNA or siRNA delivery.
• Biomimetic Membrane Research: Used to create stable, model cell membranes for studying membrane protein interactions, permeability, and cellular signaling processes.
• Surface Functionalization: Employed to modify surfaces with biomimetic coatings to enhance biocompatibility of medical devices or create specific interactive platforms for biosensors.
• Stabilizing Agent: Acts as an emulsifier or stabilizer in complex cosmetic and dermatological formulations requiring high skin compatibility.
• Gene Therapy Research: A candidate material for non-viral vector systems, facilitating the encapsulation and cellular uptake of genetic material.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	3-Octadecyloxy-2-Methoxypropylphosphonocholine
CAS No.	144615-60-1
Molecular Formula	C₂₇H₅₈NO₆P
Molecular Weight	523.73 g/mol
Synonyms	O-Octadecyl-O'-(2-methoxypropyl)phosphonocholine; 2-Methoxy-3-(octadecyloxy)propylphosphonocholine; Phosphocholine derivative C18; 1-Octadecyl-2-methoxy-glycero-3-phosphocholine analog; Synthetic C18 Ether Lipid; Lipid 144615-60-1; MPC-18 (common abbreviation)
EINECS	Contact for details

Quality Control

Every batch of 3-Octadecyloxy-2-Methoxypropylphosphonocholine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider sealing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.