Description

4-Nitrophenyl n-(Succinyl-Alanyl-Alanyl-Prolylmethyl)-n-Isopropylcarbamate is a specialized synthetic peptide derivative designed for advanced biochemical research and pharmaceutical development. This compound serves as a critical building block or intermediate in the synthesis of more complex molecules, particularly those targeting protease activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, enzymology studies, and the development of novel therapeutic agents.

Application

• Protease Inhibitor Research: Acts as a key intermediate or model substrate in the study of serine and cysteine proteases.
• Pharmaceutical Intermediate: Used in the synthesis of potential drug candidates, especially those targeting enzymatic pathways.
• Biochemical Assay Development: Employed in the design and validation of high-throughput screening assays for enzyme activity.
• Peptide Chemistry: Serves as a protected peptide fragment for solid-phase or solution-phase peptide synthesis.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and biochemistry.
• Reference Standard: Can be used as a chromatographic or spectroscopic standard for quality control in related synthetic processes.

Basic Information

Product Name	4-Nitrophenyl n-(Succinyl-Alanyl-Alanyl-Prolylmethyl)-n-Isopropylcarbamate
CAS No.	144597-19-3
Molecular Formula	C26H36N4O9
Molecular Weight	548.59 g/mol
Synonyms	4-Nitrophenyl N-(3-{[(2S)-1-[(2S)-2-[(3S)-2-({[(2,5-Dioxopyrrolidin-1-yl)oxy]carbonyl}amino)-1-oxopropan-2-yl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino}-3-oxopropyl)-N-isopropylcarbamate; N-Succinyl-Ala-Ala-Pro-methyl-4-nitroanilide derivative; Protease Substrate Intermediate; Suc-AAP-methyl-4-nitroanilide carbamate; 144597-19-3; Ala-Ala-Pro Methyl Ester 4-Nitrophenyl Carbamate Derivative
EINECS	Contact for details

Quality Control

Our 4-Nitrophenyl n-(Succinyl-Alanyl-Alanyl-Prolylmethyl)-n-Isopropylcarbamate is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all relevant specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.