Description

1-(1Z-Octadecenyl)-2-Oleoyl-Sn-Glycero-3-Phosphoethanolamine is a synthetic, high-purity phospholipid analog designed for advanced research and formulation applications. This compound is valued for its unique structural properties, which make it an essential component in the development of sophisticated lipid-based delivery systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for creating stable, functionalized vesicles and membranes.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural lipid for constructing stable, targeted drug delivery vehicles for mRNA, siRNA, and small molecule therapeutics.
• Membrane Biophysics Research: Used as a model phospholipid to study membrane fluidity, phase behavior, and protein-lipid interactions in artificial bilayer systems.
• Diagnostic Reagent Development: Serves as a functional component in the formulation of contrast agents or assay reagents for medical diagnostics.
• Biomimetic Coatings & Materials: Incorporated into surface coatings to create biocompatible, cell-membrane mimicking interfaces for medical devices and implants.
• Cryopreservation Media: Acts as a protective agent in formulations designed to preserve cell integrity during freezing and thawing cycles.
• Cosmetic Actives Delivery: Employed in high-end cosmetic formulations to enhance the stability and skin penetration of active ingredients.

Basic Information

Product Name	1-(1Z-Octadecenyl)-2-Oleoyl-Sn-Glycero-3-Phosphoethanolamine
CAS No.	144371-68-6
Molecular Formula	C59H114NO8P
Molecular Weight	980.52 g/mol
Synonyms	1-O-(1Z-Octadecenyl)-2-O-oleoyl-sn-glycero-3-phosphoethanolamine; 1-(1Z-Octadecenyl)-2-oleoyl-phosphatidylethanolamine; Plasmenyl-PE (18:1/18:1); 1-(1Z-Octadecenyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine; 1-O-(1Z-Octadecenyl)-2-oleoyl-sn-glycero-3-phosphoethanolamine; 1-(1Z-Octadecenyl)-2-oleoyl-GPE; 1-Alkenyl-2-oleoyl-sn-glycero-3-phosphoethanolamine; Plasmenylethanolamine (18:1/18:1)
EINECS	Contact for details

Quality Control

Our 1-(1Z-Octadecenyl)-2-Oleoyl-Sn-Glycero-3-Phosphoethanolamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and GMP-grade applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in chloroform, ethanol; forms dispersions in aqueous buffers
Heavy Metals	< 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.