Description

(2-Acetoxy-3-Octadecyloxy)Propyl-1-Phosphocholine is a high-purity synthetic phospholipid derivative, a key intermediate in advanced lipid research and formulation. This compound is critical for developing novel drug delivery systems, particularly liposomal and nanoparticle-based carriers for targeted therapies. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors seeking to enhance the stability and efficacy of lipid-based formulations.

Application

• Liposomal Drug Delivery: A crucial building block for synthesizing functionalized phospholipids used in the creation of stealth or targeted liposomes for cancer therapy and vaccine delivery.
• Biomimetic Membrane Research: Used in the study of membrane biophysics and the construction of model cell membranes for investigating protein-lipid interactions.
• Pharmaceutical Intermediates: Serves as a key synthetic precursor for the production of more complex, bioactive phospholipids and lipid conjugates.
• Nanoparticle Formulation: Employed in the surface functionalization of lipid nanoparticles (LNPs) and other nanocarriers to improve biocompatibility and cellular uptake.
• Diagnostic Agent Development: Utilized in the design of contrast agents and probes for medical imaging techniques like MRI and fluorescence imaging.
• Cosmetic Actives Delivery: Incorporated into advanced cosmetic formulations to enhance the skin penetration and stability of active ingredients.

Basic Information

Item	Details
Product Name	(2-Acetoxy-3-Octadecyloxy)Propyl-1-Phosphocholine
CAS No.	144260-35-5
Molecular Formula	C28H58NO7P
Molecular Weight	551.73 g/mol
Synonyms	1-O-(2-Acetoxy-3-octadecyloxy)propyl-2-hydroxy-3-(trimethylammonio)propyl phosphate; 1-O-(2-Acetyl-3-stearyloxy)propyl-2-hydroxy-3-(trimethylammonio)propyl phosphate; Phosphocholine derivative, C18-acetoxy; Lyso-PAF C18 acetate analog; Glycerophosphocholine derivative; Synthetic phospholipid intermediate; Lipid A analog precursor
EINECS	Contact for details

Quality Control

Every batch of (2-Acetoxy-3-Octadecyloxy)Propyl-1-Phosphocholine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.