Description

Toluene-4-Sulfonic Acid 2-(2-Benzyloxycarbonylamino-Ethoxy)-Ethyl Ester is a specialized organic synthetic intermediate featuring a protected aminoethoxy linker and a sulfonate ester group. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by fine chemical manufacturers and R&D laboratories engaged in creating novel active pharmaceutical ingredients (APIs), prodrugs, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring amino acid or peptide-like linkers.
• Prodrug Development: Used to create prodrug candidates where the sulfonate ester moiety aids in controlled drug release and bioavailability enhancement.
• Peptide Mimetics & Conjugates: Serves as a versatile spacer or linker molecule in the construction of peptide mimetics and antibody-drug conjugates (ADCs).
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent for synthesizing specialty polymers with tailored properties.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and tools for studying biological processes.
• Fine Chemical Synthesis: Utilized as a building block for creating complex organic molecules in custom synthesis and process development.

Basic Information

Product Name	Toluene-4-Sulfonic Acid 2-(2-Benzyloxycarbonylamino-Ethoxy)-Ethyl Ester
CAS No.	144208-62-8
Molecular Formula	C19H23NO7S
Molecular Weight	409.45 g/mol
Synonyms	2-[2-[[(Benzyloxy)carbonyl]amino]ethoxy]ethyl 4-methylbenzenesulfonate; 4-Toluenesulfonic Acid 2-[2-[(Benzyloxycarbonyl)amino]ethoxy]ethyl Ester; Tos-PEG2-Cbz-NH2; Cbz-NH-PEG2-OTs; N-Carbobenzoxy-2,2'-(ethylenedioxy)diethylamine 4-toluenesulfonate; Benzyl N-[2-(2-hydroxyethoxy)ethyl]carbamate 4-methylbenzenesulfonate
EINECS	Contact for details

Quality Control

Our Toluene-4-Sulfonic Acid 2-(2-Benzyloxycarbonylamino-Ethoxy)-Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.