Description

(S)-2-Hydroxybutyl p-Tosylate is a high-purity chiral building block and synthetic intermediate, specifically the (S)-enantiomer of the tosylate ester of 2-hydroxybutane. This compound is of significant value in asymmetric synthesis and pharmaceutical research due to its defined stereochemistry and reactive tosylate leaving group. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the construction of complex chiral molecules.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key building block for the preparation of active pharmaceutical ingredients (APIs) requiring specific (S)-configuration.
• Asymmetric Catalyst and Ligand Preparation: Used in the synthesis of chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Research: Serves as a precursor for developing chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Flavor/Fragrance Synthesis: Employed in the production of enantiomerically pure specialty chemicals, flavors, and aromas.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic synthesis and stereochemistry studies.
• Polymer Science: Potential monomer or initiator for creating polymers with chiral centers or specific tacticity.

Basic Information

Product Name	(S)-2-Hydroxybutyl p-Tosylate
CAS No.	143731-32-2
Molecular Formula	C11H16O4S
Molecular Weight	244.31 g/mol
Synonyms	(S)-2-Hydroxybutyl 4-methylbenzenesulfonate; (S)-1-Butanol, 2-, 4-methylbenzenesulfonate; (S)-2-Butanol, tosylate; (S)-sec-Butyl tosylate; p-Toluenesulfonic acid (S)-2-hydroxybutyl ester; (S)-2-Tosyloxybutane; (S)-2-OTs-butane
EINECS	Contact for details

Quality Control

Our (S)-2-Hydroxybutyl p-Tosylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and enantiomeric excess (e.e.) suitable for demanding synthetic applications. Certificates of Analysis (COA) are provided with each shipment, detailing specifications such as assay, chiral purity (by chiral HPLC or GC), and impurity profiles. We adhere to cGMP principles where applicable to ensure supply chain integrity and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.