Description

4-Isothiocyanatobenzenesulfonic Acid, Sodium Salt Monohydrate is a key chemical intermediate featuring both a reactive isothiocyanate group and a water-solubilizing sulfonate moiety. This dual functionality makes it a valuable building block for the synthesis of sulfonated derivatives, particularly in the development of labeling reagents and conjugation chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors for creating fluorescent probes, affinity labels, and other bioactive conjugates.

Application

• Fluorescent Probe Synthesis: Acts as a reactive linker for attaching fluorophores to biomolecules like proteins and antibodies for diagnostic assays and imaging.
• Affinity Labeling Reagents: Used to create sulfonated chemical probes that target specific enzymes or receptors in biochemical research.
• Protein Conjugation & Modification: Enables the site-specific modification of peptides and proteins to alter their solubility or introduce functional handles.
• Diagnostic Kit Manufacturing: A critical raw material in the production of components for clinical diagnostic tests and kits.
• Life Science Research: Employed in academic and industrial R&D for developing novel bio-conjugates and molecular tools.
• Chromatography Reagents: Can be used to synthesize specialized ligands or stationary phases for separation techniques.

Basic Information

Product Name	4-Isothiocyanatobenzenesulfonic Acid, Sodium Salt Monohydrate
CAS No.	143193-53-7
Molecular Formula	C7H5NNaO4S2 • H2O
Molecular Weight	279.25 g/mol (Monohydrate)
Synonyms	Benzenesulfonic acid, 4-isothiocyanato-, sodium salt, monohydrate; Sodium 4-isothiocyanatobenzenesulfonate monohydrate; 4-Isothiocyanatobenzenesulfonate sodium salt hydrate; p-Isothiocyanatobenzenesulfonic acid sodium salt; SCBN; ITSBS sodium salt; 4-Sulfophenyl isothiocyanate sodium salt
EINECS	Contact for details

Quality Control

Our 4-Isothiocyanatobenzenesulfonic Acid, Sodium Salt Monohydrate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	5.0 - 8.0%
Heavy Metals	< 20 ppm
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.