Description

n-Ethoxycarbonyl-7-Oxostaurosporine is a chemically modified derivative of the potent kinase inhibitor staurosporine, designed for advanced research applications. This compound serves as a critical intermediate and a valuable tool compound in the development of novel therapeutic agents targeting specific protein kinases. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies engaged in oncology and signal transduction pathway studies. Its defined structure allows for precise investigation into kinase inhibition mechanisms and structure-activity relationships.

Application

• Pharmaceutical Research & Development: A key intermediate in the synthesis of novel, targeted kinase inhibitors for potential cancer therapies.
• Biochemical Assay Development: Used as a reference standard and probe compound in high-throughput screening (HTS) campaigns to identify new drug candidates.
• Mechanistic Studies: Employed in academic and industrial labs to study cellular signaling pathways, apoptosis, and protein kinase function.
• Medicinal Chemistry Optimization: Serves as a scaffold for further chemical modification to improve potency, selectivity, and pharmacokinetic properties of drug leads.
• Preclinical Research: Utilized in *in vitro* and cell-based studies to validate new therapeutic targets in oncology and other disease areas.

Basic Information

Product Name	n-Ethoxycarbonyl-7-Oxostaurosporine
CAS No.	143086-33-3
Molecular Formula	C30H27N4O5
Molecular Weight	523.56 g/mol
Synonyms	7-Oxo-7-deoxy-ethoxycarbonylstaurosporine; UCN-01 Ethoxycarbonyl Derivative; CEP-701 Intermediate; Ethyl 7-oxostaurosporine Carbamate; 1-Ethoxycarbonyl-7-oxostaurosporine; K-252a Derivative; Research Compound 143086-33-3; Staurosporine analog
EINECS	Contact for details

Quality Control

Our n-Ethoxycarbonyl-7-Oxostaurosporine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use, the material may be stored at 2-8°C. The compound is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.