Description

2,3-o-Bis(10,12-Tricosadiynyl)Glycero-1-Phosphocholine (CAS NO 143062-81-1) is a specialized synthetic phospholipid derivative, engineered for advanced research and material science applications. This compound is valued for its unique diacetylene-functionalized lipid chains, which enable polymerization and the creation of stable, responsive biomimetic membranes. It is primarily sought by researchers and product developers in the fields of nanotechnology, biosensor development, and advanced drug delivery systems.

Application

• Polymerizable Lipid Bilayer Research: Key component for creating photopolymerizable or thermally polymerizable model membranes to study membrane dynamics and stability.
• Biosensor Fabrication: Used to develop stable, functionalized lipid layers on sensor surfaces for detecting biological interactions.
• Advanced Drug Delivery Vesicles: Serves as a building block for constructing stimuli-responsive liposomes and nanoparticles that release cargo upon specific triggers.
• Biomimetic Material Science: Integral in synthesizing novel materials that mimic biological membrane properties for tissue engineering and synthetic biology.
• Photonic and Electronic Device Research: Explored for its potential in creating organic electronic components and colorimetric sensors due to its diacetylene chromophores.
• Basic Biochemical and Biophysical Studies: Utilized as a tool to investigate lipid-protein interactions, membrane fusion, and cellular signaling processes in controlled environments.

Basic Information

Product Name	2,3-o-Bis(10,12-Tricosadiynyl)Glycero-1-Phosphocholine
CAS No.	143062-81-1
Molecular Formula	C56H100NO8P
Molecular Weight	946.37 g/mol
Synonyms	1,2-Bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine; Diyne PC; Polymerizable Phosphatidylcholine; 23:2 Diyne PC; Bis-Tricosadiynoyl Phosphatidylcholine; PCDA Lipid; Photopolymerizable Lipid; (2,3-Bis(10,12-tricosadiynoyloxy)propyl) 2-(trimethylammonio)ethyl phosphate
EINECS	Contact for details

Quality Control

Every batch of 2,3-o-Bis(10,12-Tricosadiynyl)Glycero-1-Phosphocholine is produced and analyzed under strict quality protocols to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Our quality commitment includes comprehensive analytical characterization. Certificates of Analysis (COA) detailing purity, identity, and critical specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Due to its hygroscopic nature, the container must be sealed immediately after use to minimize exposure to atmospheric moisture. For long-term stability, avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (Phosphorus)	≥ 98% of theoretical
Solubility	Soluble in chloroform, DCM; forms vesicles in aqueous buffers
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.