Description

1,2-Bis(10-(2',4'-Hexadienoyloxy)Decyl)Glycero-3-Phosphocholine is a specialized synthetic phospholipid derivative, a key building block in advanced lipid research and formulation. This compound matters for its role as a functionalized lipid, enabling the creation of precisely engineered liposomes and lipid nanoparticles for targeted delivery systems. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors developing next-generation drug delivery platforms, diagnostic agents, and biomimetic membranes.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A critical component for constructing functionalized vesicles for drug and gene delivery (e.g., mRNA vaccines, siRNA therapeutics).
• Targeted Drug Delivery Systems: The reactive dienoyl groups allow for further chemical conjugation with targeting ligands (e.g., antibodies, peptides) to achieve cell-specific targeting.
• Biomimetic Membrane Research: Used to create model membranes with tailored properties for studying membrane dynamics, protein-lipid interactions, and permeability.
• Diagnostic Agent Encapsulation: Employed in the development of contrast agents for medical imaging (e.g., ultrasound, MRI) by providing a stable, functionalizable lipid shell.
• Surface Modification of Biomaterials: Can be used to coat surfaces to create biocompatible or stealth coatings for medical implants and devices.
• Chemical Biology and Probe Development: Serves as a precursor for synthesizing photoactivatable or click-chemistry compatible lipid probes for cellular tracking studies.

Basic Information

Item	Detail
Product Name	1,2-Bis(10-(2',4'-Hexadienoyloxy)Decyl)Glycero-3-Phosphocholine
CAS No.	143023-08-9
Molecular Formula	C48H86NO12P
Molecular Weight	900.18 g/mol
Synonyms	1,2-Di-(10-(2',4'-hexadienoyloxy)decyl)-sn-glycero-3-phosphocholine; Dienoyl-PC; Phosphatidylcholine, 1,2-bis[10-[(2E,4E)-2,4-hexadienoyloxy]decyl]-; Functionalized Phospholipid; Conjugatable Lipid; Reactive Phosphatidylcholine; (2',4'-Hexadienoyloxy)Decyl Modified PC; Lipid Anchor with Dienoyl Group
EINECS	Contact for details

Quality Control

Every batch of 1,2-Bis(10-(2',4'-Hexadienoyloxy)Decyl)Glycero-3-Phosphocholine is produced and analyzed under strict quality protocols to ensure identity, purity, and consistency for sensitive research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, impurity profile, and specific analytical data (NMR, HPLC) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) and easily oxidized nature, store under an inert atmosphere (argon or nitrogen) at -20°C or below for long-term stability. For short-term use, store desiccated at 2-8°C. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0 %
Solvent Residue (GC)	Meets ICH guidelines
Phosphorus Assay	Theoretical ± 2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.