Description

5-Oxo-15-Hydroxy-6,8,11,13-Eicosatetraenoic Acid is a specialized eicosanoid derivative, a key intermediate in the lipoxygenase pathway of arachidonic acid metabolism. This compound is of significant interest for its role as a precursor in the biosynthesis of various bioactive lipid mediators, including lipoxins and hepoxilins. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for drug discovery, biochemical research, and the development of analytical standards.

Application

• Biochemical Research: Used as a critical reference standard and intermediate in studies of eicosanoid biosynthesis, inflammation pathways, and lipid signaling.
• Pharmaceutical Development: Serves as a key starting material or intermediate in the synthesis of novel anti-inflammatory agents and lipid-based therapeutics.
• Analytical Chemistry: Employed as a high-purity standard for method development and quantification in HPLC, LC-MS, and other analytical techniques.
• Enzyme Substrate: Acts as a substrate for studying the activity and inhibition of lipoxygenase and other related enzymes.
• Cell Signaling Studies: Utilized in cellular assays to investigate the effects of specific eicosanoid metabolites on cell function and communication.

Basic Information

Product Name	5-Oxo-15-Hydroxy-6,8,11,13-Eicosatetraenoic Acid
CAS No.	142828-12-4
Molecular Formula	C₂₀H₃₀O₅
Molecular Weight	350.45 g/mol
Synonyms	5-Oxo-15(S)-HETE; 5-oxo-15S-hydroxy-6E,8Z,11Z,13E-eicosatetraenoic acid; 15(S)-HETE-5-one; 5-Keto-15-hydroxy-6,8,11,13-eicosatetraenoic acid; 5-Oxo-15S-HETE; 15S-Hydroxy-5-oxo-6,8,11,13-eicosatetraenoic acid; 5-Oxo-15-hydroxy-EET
EINECS	Contact for details

Quality Control

Our 5-Oxo-15-Hydroxy-6,8,11,13-Eicosatetraenoic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content	≤ 1.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.