Description

4-Nitrophenyl Myo-Inositol-1-Phosphate, Ammonium Salt is a specialized biochemical reagent, a chromogenic substrate for phosphatidylinositol-specific phospholipase C (PI-PLC) and other inositol phosphate phosphatases. Its core value lies in enabling sensitive, colorimetric assays for enzyme activity, crucial for biochemical research and drug discovery targeting inositol signaling pathways. This compound is essential for researchers and manufacturers in pharmaceutical R&D, diagnostic kit production, and academic biochemistry laboratories studying phosphoinositide metabolism.

Application

• Enzyme Activity Assays: Primary substrate for colorimetric detection of Phosphatidylinositol-specific Phospholipase C (PI-PLC) activity.
• Biochemical Research: Tool compound for studying inositol phosphate signaling pathways, second messenger systems, and cellular regulation.
• Drug Discovery Screening: Used in high-throughput screening (HTS) platforms to identify and characterize inhibitors or activators of inositol phosphate-metabolizing enzymes.
• Diagnostic Development: Key component in developing in-vitro diagnostic (IVD) tests for conditions linked to phosphoinositide pathway dysregulation.
• Academic & Industrial R&D: Fundamental reagent for investigating lipid biochemistry, signal transduction, and molecular biology in both academic and industrial settings.

Basic Information

Product Name	4-Nitrophenyl Myo-Inositol-1-Phosphate, Ammonium Salt
CAS No.	142741-72-8
Molecular Formula	C12H19N2O11P
Molecular Weight	398.26 g/mol
Synonyms	PNP-Inositol-1-Phosphate, Ammonium Salt; 4-Nitrophenyl myo-Inositol 1-Phosphate Ammonium Salt; 1D-myo-Inositol 1-(4-Nitrophenyl phosphate) Ammonium Salt; PNP-α-D-myo-Inositol 1-Phosphate; 4-NPP-Inositol-1-P, NH4+ salt; Inositol 1-Phosphate 4-Nitrophenyl Ester Ammonium Salt; Chromogenic PI-PLC Substrate
EINECS	Contact for details

Quality Control

Our 4-Nitrophenyl Myo-Inositol-1-Phosphate, Ammonium Salt is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee it meets the stringent requirements of life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, consider aliquoting to minimize freeze-thaw cycles and exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.