Description

Tauro 1-Hydroxycholic Acid is a modified bile acid derivative, specifically a taurine conjugate of 1-hydroxycholic acid. This compound is of significant interest in pharmaceutical research and development due to its role as a key intermediate and reference standard for studying bile acid metabolism and hepatobiliary function. It is primarily utilized by research institutions, pharmaceutical manufacturers, and diagnostic companies engaged in metabolic disorder studies, liver function testing, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical starting material or building block in the synthesis of more complex bile acid analogs and therapeutic agents.
• Biochemical Research: Used as a reference standard and reagent in studies of bile acid conjugation, transport, and enterohepatic circulation.
• Diagnostic Reagent Manufacturing: Employed in the production of calibrators and controls for in-vitro diagnostic (IVD) kits that assess liver function and bile acid profiles.
• Metabolic Pathway Analysis: A tool for investigating disorders related to bile acid synthesis, such as cholestasis and certain genetic metabolic diseases.
• Cell Culture & Membrane Studies: Applied in research to study the effects of bile acids on cell membranes, particularly hepatocytes and intestinal cells.
• Academic & Contract Research: Serves as a high-purity chemical for universities and CROs (Contract Research Organizations) conducting fundamental life science research.

Basic Information

Product Name	Tauro 1-Hydroxycholic Acid
CAS No.	142608-64-8
Molecular Formula	C₂₆H₄₅NO₇S
Molecular Weight	515.71 g/mol
Synonyms	1-Hydroxycholyltaurine; Tauro-1α-hydroxycholic Acid; 1α-Hydroxycholic Acid Taurine Conjugate; N-[(3α,5β,7α,12α)-1,3,7,12-Tetrahydroxy-24-oxocholan-24-yl]taurine; Taurochenodeoxycholic Acid 1-Hydroxy Derivative; T-1-HCA; 1-Hydroxy-TCA
EINECS	Contact for details

Quality Control

Our Tauro 1-Hydroxycholic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and production use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.