Description

Crambescin C1 CAS NO 142605-06-9 is a bioactive guanidine alkaloid isolated from marine sponges of the genus *Crambe*. This compound matters as a potent and selective inhibitor of voltage-gated sodium channels, making it a valuable tool for neurological and pharmacological research. It is needed by researchers in neuroscience, pharmaceutical development, and academic institutions for studying ion channel function, pain pathways, and for use as a reference standard in analytical chemistry.

Application

• Neuroscience Research: As a selective sodium channel blocker for studying neuronal excitability and signal transduction.
• Pharmacological Tool Compound: Used in high-throughput screening and target validation for drug discovery programs focused on pain, epilepsy, and cardiac arrhythmias.
• Analytical Reference Standard: For quality control and method development in HPLC, LC-MS, and other analytical techniques within pharmaceutical and contract research organizations.
• Marine Natural Product Studies: Serves as a chemical marker or lead compound in marine biodiscovery and bioactivity assays.
• Academic & Institutional Research: For fundamental studies in chemical ecology, toxicology, and ion channel biophysics.

Basic Information

Product Name	Crambescin C1
CAS No.	142605-06-9
Molecular Formula	C23H40N6O4
Molecular Weight	464.60 g/mol
Synonyms	Crambescin C1; Crambescin C; (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-5-guanidino-pentanoyl]amino]-5-guanidino-pentanoyl]amino]-5-guanidino-pentanoyl]amino]pentanedioic acid; Marine alkaloid C1; Sodium channel inhibitor from Crambe sp.
EINECS	Contact for details

Quality Control

Our Crambescin C1 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and structural confirmation via NMR and MS, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain quality.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.